HCLPearls®

Reproducibility and repetability using Hepatic Cell Lines

Keep all the advantages, just change the cell line!

Derived directly from HepatoPearls®, our HCLPearls®(Hepatic Cell Line) consist in encapsulation of differentiated HepaRG®, known as HPR-116 cells.

HPR116 cells display all the hallmarks of hepatocytes. Their common genetic background ensures high reproducibility and repetability between your experiments.

Main features:

Extended lifespan: more than a month and a half to run your experiments

A model for CYP induction studies…

NT = Non Treated, Rif = Rifampicine, Omep = Omperazole - DMSO is the vehicle

Organized architecture:
Presence of biliary pockets

… and hepatoxicity